Abstract
Correlation of Cigarette Smoking to Differential Leukocyte
Fritzwarren Recto, Mary Rose Akiatan, Sittie Radjiva Bayabao,
Jane Whila Cuizon, Joanna Marie Revil,
Evangeline M. Señedo, Nelfa D. Canini
The relation between cigarette smoking and differential leukocyte count has
not been well described. The present study was carried out to observe the
changes in total and differential count of white blood cells of clinically
healthy smokers in Ozamiz City, Philippines. Simple random sampling
was used in selecting the healthy 30 smokers (15 male, 15 female) and
30 non-smokers (15 male, 15 female) from the target group. Standard blood
collection procedure was utilized and blood samples were analyzed using
SysmexXS-1000i. Results showed a significant increase in the total
leukocyte count of smokers. Granulocytes and monocytes levels were
significantly higher in smokers compared to the non-smokers. Among the
granulocytes, there was a significant increase in eosinophil count in smokers,
whereas the neutrophils were significantly lower. The lymphocyte and
basophils were not significantly affected by smoking. The number of
cigarettes smoked and number of days of smoking are positively correlated
with the total leucocyte count. Cigarette smoking is associated with
alterations in inflammatory markers among smokers.
KEYWORDS: eosinophils, granulocytes, monocytes, neutrophils, smokers
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