Indigenous microorganisms (IMO) 7 is an organic fertilizer produced from a series of aerobic and anaerobic fermentations. This study investigated the effects of levels of indigenous microorganisms (IMO) 7 such as control (N:P:K: 120:90:60), IMO 7 at 7.5 t ha-1 , 15 t ha-1 , and 22.5 t ha-1 and organic nutrient supplements (ONS) - fish amino acid (FAA), fermented plant juice (FPJ), and fermented seaweed (FS) on the different agronomic, physiological and economic parameters of sweet corn. The experimental plots were arranged using a 4 x 4 factorial in Randomized Complete Block Design (RCBD) with three replicates. The results revealed that the IMO 7 significantly improved the ear height, net assimilation rate (NAR) 55-65 days after planting (DAP), dry matter yield (DMY), and return on investment (ROI). The ONS influenced the ear yield, leaf area index (LAI) at 65 DAP, NAR (45-55, and 55-65 DAP), and ROI. The control (N:P:K: 120:90:60), and the IMO 7 at 22.5 t ha-1 gave the highest DMY 10.58 and 10.37 t ha-1 , respectively. Among the ONS, FS obtained the highest ear yield at 13 t ha-1 and NAR of 0.091 - 0.131 gm-2 day-1 . Economically, control (N:P:K: 120:90:60) achieved the highest ROI at 392.1%, followed by IMO 7 at 7.5 t ha-1 at 287%. FS got the highest ROI at 269.8% among the ONS. The results provide vital information on IMO 7 and ONS's effects on sustainable sweet corn production in Aurora, Zamboanga del Sur, Philippines.